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However, a largeplacebo-controlled trial of US high-risk women did notshow any effect of the combination of folic acid, vitaminB6 and B12 on stroke or total cardiovascular events after7.3 years (Albert et al., 2008).
The action cannot bebroadly labelled as catabolic or anabolic. The amount of melanin accounts for the color differ-ences in skin.
The credibility of the trial depends onthe measures that are taken to minimize bias.
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